Indications
- Gastroesophageal Reflux Disease (GERD): Reduces acid reflux and helps alleviate symptoms such as heartburn, chest discomfort, and regurgitation.
- Dyspepsia (Indigestion): Relieves symptoms like bloating, early satiety, and discomfort due to impaired gastric motility.
- Erosive Esophagitis: Heals esophageal inflammation caused by acid reflux.
- Peptic Ulcers: Assists in healing stomach and duodenal ulcers by reducing stomach acid and improving gastric motility.
- Delayed Gastric Emptying: Domperidone enhances gastric motility, helping reduce symptoms of nausea, fullness, and bloating.
- Nausea and Vomiting: Effectively manages nausea and vomiting due to gastrointestinal causes.
Dosage and Administration
Route of Administration: Oral tablet.
Typical Dose for Adults: One tablet daily, preferably 30 minutes before a meal, or as directed by a healthcare provider.
Administration: Swallow the tablet whole with water. Do not chew, crush, or split the tablet to ensure proper absorption and effectiveness.
Duration of Therapy: The treatment duration will vary depending on the condition being treated and should be determined by a healthcare provider.
Precautions
Hypersensitivity: Avoid use in patients allergic to Esomeprazole, Domperidone, or any other ingredients of the formulation.
Pregnancy and Breastfeeding: Use during pregnancy and breastfeeding should be under medical supervision, and only if the benefits outweigh the risks.
Liver or Kidney Disease: Use with caution in patients with liver or kidney impairment. Dose adjustments may be necessary.
Cardiac Conditions: Domperidone may increase the risk of QT prolongation, so it should be used with caution in patients with heart disease or those on other medications that affect the QT interval.
Prolonged Use: Long-term use of Esomeprazole may increase the risk of vitamin B12 deficiency, magnesium deficiency, and bone fractures. Regular monitoring is advised for extended use.
Benefits
Dual Action: Esomeprazole reduces stomach acid production, while Domperidone enhances gastric motility, offering comprehensive relief from acid reflux and digestive discomfort.
Improves Digestion: Helps alleviate nausea, bloating, and fullness associated with delayed gastric emptying.
Convenient Dosage: One tablet daily, making it easy to follow a treatment regimen.
Relieves GERD Symptoms: Reduces heartburn, chest pain, and regurgitation associated with acid reflux.
Effective for Indigestion: Provides relief from bloating and other dyspeptic symptoms, improving overall digestion.