Omvas-D
OMVAS-D is a combination capsule containing Esomeprazole, a proton pump inhibitor (PPI), and Domperidone, a prokinetic agent. This sustained-release (SR) formulation is designed to provide comprehensive relief from acid-related gastrointestinal disorders while also addressing motility issues, such as delayed gastric emptying and nausea.
- Recommended Usage
Indications
- Gastroesophageal Reflux Disease (GERD): Reduces acid reflux and alleviates symptoms like heartburn, chest discomfort, and regurgitation.
- Dyspepsia (Indigestion): Provides relief from bloating, nausea, and early satiety due to gastric motility disorders.
- Erosive Esophagitis: Heals esophageal inflammation caused by acid reflux.
- Peptic Ulcers: Aids in the healing of stomach and duodenal ulcers by reducing stomach acid and improving gastric motility.
- Delayed Gastric Emptying: Domperidone helps improve gastric motility, reducing symptoms of nausea, bloating, and fullness.
- Nausea and Vomiting: Effective in controlling nausea and vomiting due to gastrointestinal disturbances.
Dosage and Administration
Route of Administration: Oral sustained-release capsule.
Typical Dose for Adults: One capsule daily, preferably 30 minutes before a meal, or as prescribed by a healthcare provider.
Administration: Swallow the capsule whole with water. Do not chew, crush, or split the capsule to ensure sustained-release action.
Duration of Therapy: The duration of use should be determined by a healthcare provider based on the condition being treated.
Precautions
Hypersensitivity: Avoid use in patients allergic to Esomeprazole, Domperidone, or any other components of the formulation.
Pregnancy and Breastfeeding: Use during pregnancy and breastfeeding should only be considered if the potential benefit outweighs the risks, under the guidance of a healthcare provider.
Liver or Kidney Disease: Use with caution in patients with liver or kidney impairment. Dose adjustments may be necessary.
Cardiac Conditions: Domperidone may increase the risk of QT prolongation. It should be used cautiously in patients with heart disease or those taking other medications that can affect the QT interval.
Prolonged Use: Long-term use of PPIs like Esomeprazole may increase the risk of vitamin B12 deficiency, magnesium deficiency, and bone fractures. Regular monitoring may be needed during extended use.
Benefits
Dual Action: Esomeprazole effectively suppresses stomach acid production, while Domperidone improves gastric motility, addressing both acid reflux and digestive discomfort.
Sustained-Release Formula: Provides long-lasting symptom relief throughout the day.
Comprehensive Gastrointestinal Relief: Ideal for conditions like GERD, peptic ulcers, and motility disorders.
Improves Digestion: Reduces symptoms of nausea, bloating, and fullness caused by delayed gastric emptying.
Convenient Administration: One capsule daily offers ease of use and better adherence to treatment.
