Indications
- Gastroesophageal Reflux Disease (GERD): Treats acid reflux and associated symptoms such as heartburn, regurgitation, and nausea.
- Dyspepsia (Indigestion): Provides relief from bloating, nausea, and early satiety associated with impaired gastric motility.
- Erosive Esophagitis: Reduces esophageal inflammation caused by acid reflux.
- Delayed Gastric Emptying: Itopride enhances gastric motility, helping to relieve symptoms of nausea and fullness.
- Functional Dyspepsia: Improves overall digestive function by addressing both acid secretion and motility issues.
Dosage and Administration
Route of Administration: Oral sustained-release capsule.
Typical Dose for Adults: One capsule daily, preferably 15-30 minutes before a meal, or as prescribed by a healthcare provider.
Administration: Swallow the capsule whole with water. Do not chew, crush, or split the capsule to maintain the sustained-release action.
Precautions
Hypersensitivity: Avoid use in patients allergic to rabeprazole, itopride, or other components of the formulation.
Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy and breastfeeding.
Drug Interactions: May interact with medications that affect the liver enzyme system (CYP450), other gastric acid suppressors, or prokinetic drugs.
Liver or Kidney Disease: Use cautiously in patients with significant hepatic or renal impairment, as both Rabeprazole and Itopride require dose adjustments in these conditions.
Prolonged Use: Extended use of PPIs (such as Rabeprazole) may increase the risk of vitamin B12 deficiency, magnesium deficiency, and bone fractures.
Benefits
Dual Mechanism of Action: Rabeprazole provides effective acid suppression, while Itopride enhances gastric motility, improving overall digestion.
Sustained-Release Formula: Ensures continuous, long-lasting relief throughout the day.
Comprehensive Digestive Relief: Treats both acid reflux and motility issues in conditions like GERD and functional dyspepsia.
Improves Gastric Emptying: Itopride addresses delayed gastric emptying, reducing symptoms of bloating, nausea, and fullness.
Well-Tolerated: Minimal side effects when taken as prescribed.