Unispas
UNISPAS is a combination tablet that combines two active ingredients: dicyclomine, an antispasmodic, and mefenamic acid, a nonsteroidal anti-inflammatory drug (NSAID). This combination is used to provide relief from abdominal pain and discomfort associated with gastrointestinal disorders, such as irritable bowel syndrome (IBS) and dysmenorrhea (painful menstruation).
- Recommended Usage
Indications
Irritable Bowel Syndrome (IBS): For abdominal cramps and discomfort associated with IBS.
Dysmenorrhea (Painful Menstruation): For the relief of menstrual cramps and associated pain.
Abdominal Spasms: For conditions causing abdominal cramping, such as colic and other gastrointestinal discomforts.
Dosage and Administration
Route of Administration: Oral tablet.
Typical dose for adults:
o Irritable Bowel Syndrome (IBS): 1 tablet (10 mg dicyclomine, 250 mg mefenamic acid) 2-3 times daily.
o Dysmenorrhea (Menstrual Pain): 1 tablet every 6-8 hours as needed during pain episodes.
Maximum Dose: Do not exceed 3 tablets per day.
Administration: Take the tablet with or without food, and swallow whole. If you experience stomach upset, consider taking it with food.
Precautions
Gastrointestinal Disorders: Use with caution in patients with a history of gastrointestinal bleeding, ulcers, or other serious GI conditions.
Liver and Kidney Function: Caution is advised in patients with liver or kidney impairment, as NSAIDs can affect these organs.
Heart Disease: Mefenamic acid (NSAID) can increase the risk of heart problems, so use cautiously in patients with a history of cardiovascular disease.
Dehydration: Dicyclomine may cause dry mouth, dizziness, and blurred vision; take care when driving or operating machinery.
Avoid in Pregnancy: Not recommended during the third trimester of pregnancy due to potential risks to the fetus. Consult with a healthcare provider before use during the first two trimesters.
Breastfeeding: Consult a doctor before use, as both active ingredients can pass into breast milk.
Contraindications
Hypersensitivity: Contraindicated in patients with known hypersensitivity to dicyclomine, mefenamic acid, or any other ingredients of the tablet.
Active Peptic Ulcer Disease: Due to the NSAID component (mefenamic acid), which can worsen gastrointestinal ulcers or bleeding.
Severe Heart, Liver, or kidney disease: Use is contraindicated in individuals with severe impairment of heart, liver, or kidney function.
Dehydration or Obstruction: Contraindicated in patients with urinary or gastrointestinal tract obstruction.
Glaucoma: Dicyclomine may exacerbate narrow-angle glaucoma.
Key Benefits
Relieves Abdominal Cramps: Dicyclomine works by relaxing the smooth muscles in the gastrointestinal tract, which helps to relieve spasms and cramping.
Reduces Menstrual Pain: Mefenamic acid, a potent NSAID, helps reduce inflammation and alleviates menstrual cramps.
Dual Action: The combination of an antispasmodic (dicyclomine) and an NSAID (mefenamic acid) provides effective relief from both the spasm and pain aspects of gastrointestinal and menstrual discomfort.
Fast-Acting: Provides relatively quick relief from abdominal discomfort and cramping.
Convenient Dosing: Only 1-2 tablets are needed per day, depending on the severity of symptoms, making it easier to manage the condition.
