Levosulpiride 25mg Tablet
ZESTOGUT-25 contains Levosulpiride, a prokinetic agent and dopamine receptor antagonist. It is primarily used to manage gastrointestinal motility disorders and conditions related to delayed gastric emptying, such as dyspepsia and gastroesophageal reflux disease (GERD). Levosulpiride also has antidepressant and antipsychotic properties, making it beneficial for certain psychological and physical symptoms associated with gastrointestinal conditions.
- Recommended Usage
Indication
- Functional Dyspepsia: Relief from bloating, early satiety, and epigastric discomfort.
- Gastroesophageal Reflux Disease (GERD): For managing reflux symptoms by improving gastric motility.
- Irritable Bowel Syndrome (IBS): Addresses symptoms like abdominal pain and discomfort.
- Delayed Gastric Emptying: Enhances stomach emptying in conditions like diabetic gastroparesis.
- Psychosomatic Disorders: Supports treatment of symptoms associated with anxiety or depression related to gastrointestinal disorders.
Dosage and Administration
Route of Administration: Oral tablet.
Typical Dose for Adults: 25mg taken 2-3 times daily before meals, or as directed by a healthcare provider.
Administration: Swallow the tablet whole with water, preferably on an empty stomach for better efficacy.
Precautions
Prolonged Use: Long-term use should be monitored to avoid potential side effects such as tardive dyskinesia or extrapyramidal symptoms.
Pregnancy and Breastfeeding: Consult a healthcare provider before using ZESTOGUT-25 during pregnancy or while breastfeeding.
Kidney or Liver Impairment: Dose adjustments may be required for patients with renal or hepatic dysfunction.
Interactions: Avoid combining with alcohol, sedatives, or other dopamine antagonists as it may enhance drowsiness or extrapyramidal side effects.
Contraindications
Hypersensitivity: Not suitable for patients with known allergies to Levosulpiride or other sulpiride derivatives.
Epilepsy: Avoid use in patients with a history of epilepsy or seizure disorders.
Prolactin-Dependent Tumors: Contraindicated in patients with prolactinoma or other prolactin-dependent conditions.
Severe Depression: Use with caution as it may exacerbate symptoms of severe depression.
Benefits
Improves Gastric Motility: Enhances stomach emptying and reduces symptoms of bloating and fullness.
Relieves GERD Symptoms: Reduces acid reflux and associated discomfort.
Dual Action: Provides both gastrointestinal and mild psychotropic benefits for patients with somatic symptoms linked to stress or anxiety.
Symptom Relief in IBS: Helps alleviate abdominal pain and motility-related IBS symptoms.
Well-Tolerated: Generally well-tolerated with minimal side effects when taken as prescribed.
