Nebivolol
Nebivolol acts primarily by blocking beta-1 adrenergic receptors in the heart, leading to a slower heart rate and reduced force of contraction. It may also dilate blood vessels by increasing the release of nitric oxide, a naturally occurring substance in the body2.
- Recommended Usage
Usage & Indications:
Nebivolol is used for:
- Hypertension (High Blood Pressure): Helps in reducing the heart's workload and controlling blood pressure.
- Heart Failure: Supports heart function and eases symptoms of heart failure.
- Angina: Helps reduce chest pain by decreasing oxygen demand of the heart.
Dosage and Administration:
- Starting Dosage: Usually begins at 5 mg once daily, with or without food.
- Adjustment: Based on response, the dosage can be increased at 2-week intervals up to a maximum of 40 mg per day.
- Missed Dose: Take it as soon as you remember unless it's close to the next dose; do not double dose.
Precautions:
- Avoid sudden discontinuation: Risk of exacerbation of angina, heart attacks, or other serious heart issues.
- Regular Monitoring: Heart rate and blood pressure monitoring are essential during therapy.
- Caution with Asthma and Diabetes: May worsen symptoms of bronchospasm or obscure hypoglycemia3.
Contraindications:
- Severe heart conditions such as heart failure, 2nd or 3rd-degree AV block, and sick sinus syndrome (without pacemaker).
- Severe liver disease or if the heart cannot pump blood properly.
- Known allergies to ingredients in Nebivolol.
Key Benefits:
- Effective Blood Pressure Control: Proven efficacy in lowering blood pressure significantly4.
- Improves Heart Function: Leads to a beneficial reduction in the workload of the heart9.
- Fewer Side Effects: Compared to some other beta-blockers, Nebivolol may have fewer adverse effects.
- Unique Vasodilatory Properties: Can provide additional cardiovascular benefits beyond just beta-blockade.
- Support for Heart Failure: Helps in managing symptoms and improving the quality of life in heart failure patients.
